El desarrollo de la tecnociencia en los últimos decenios ha sido vertiginoso y los problemas y dilemas bioéticos que plantea a la humanidad son incontables. Sin embargo, el pensamiento bioético está recién comenzando a analizar la trascendencia de los adelantos científico-técnicos; particularmente en relación a problemáticas de frontera, tales como: las tecnologías de fertilización asistida, las investigaciones con células madre, el mantenimiento de la vida con técnicas artificiales, entre otras. Temas cardinales como la humanización de la medicina, el derecho a (...) la salud, la influencia nociva de la comercialización y la medicalización excesiva no forman parte hegemónica del discurso bioético. Es preocupante que la formación de los profesionales de salud mayoritariamente ignora la importancia de la bioética secular fundamentada en los derechos humanos, que debiera ser el eje de la capacitación para prestar atención de salud. Éste artículo se focalizará en la genómica, una rama de la tecnociencia de gran predicamento actual. (shrink)

Although organizational commitment continues to interest researchers because of its positive effects on organizations, we know relatively little about the effects of the ethical context on organizational commitment. As such, we contribute to the organizational commitment field by assessing the effects of ethical climates (Victor and Cullen, 1987, 1988) on organizational commitment. We hypothesized that an ethical climate of benevolence has a positive relationship with organizational commitment while egoistic climate is negatively related to commitment. Results supported our propositions for (...) both a benevolent climate and an egoistic climate. We also hypothesized that a principled climate is positively related to organizational commitment for professional workers but has no relationships for nonprofessional workers. Results supported this hypothesis. (shrink)

BackgroundPreprint usage is growing rapidly in the life sciences; however, questions remain on the relative quality of preprints when compared to published articles. An objective dimension of quality that is readily measurable is completeness of reporting, as transparency can improve the reader’s ability to independently interpret data and reproduce findings.MethodsIn this observational study, we initially compared independent samples of articles published in bioRxiv and in PubMed-indexed journals in 2016 using a quality of reporting questionnaire. After that, we performed paired comparisons (...) between preprints from bioRxiv to their own peer-reviewed versions in journals.ResultsPeer-reviewed articles had, on average, higher quality of reporting than preprints, although the difference was small, with absolute differences of 5.0% [95% CI 1.4, 8.6] and 4.7% [95% CI 2.4, 7.0] of reported items in the independent samples and paired sample comparison, respectively. There were larger differences favoring peer-reviewed articles in subjective ratings of how clearly titles and abstracts presented the main findings and how easy it was to locate relevant reporting information. Changes in reporting from preprints to peer-reviewed versions did not correlate with the impact factor of the publication venue or with the time lag from bioRxiv to journal publication.ConclusionsOur results suggest that, on average, publication in a peer-reviewed journal is associated with improvement in quality of reporting. They also show that quality of reporting in preprints in the life sciences is within a similar range as that of peer-reviewed articles, albeit slightly lower on average, supporting the idea that preprints should be considered valid scientific contributions. (shrink)

Se abordan dos formas de justicia en principio antagónicas: la retributiva, propia del mundo de los héroes y de la venganza antigua, y la punitiva, de tradición tanto antigua como moderna, que consiste en la racionalización de la violencia mediante el tribunal. Se muestra la preeminencia de la punitiva, el antagonismo a medias con la retributiva, que viene a ser la apropiación de la violencia por la necesidad, y su marginación del ámbito de la justicia. The article addresses two antagonistic (...) forms of justice: retributive justice, form which belongs to the world of heroes and ancient vengeance; and punitive justice, which can be found in both ancient and modern traditions and consists on the rationalization of violence by means of the court. The article shows the preeminence of the punitive justice, its half antagonism with the retributive form -which comes to be violence's appropriation made by necessity -, and its margination from justice's ambit. (shrink)

Firearm injuries are a significant public health problem. Prior studies have analyzed firearm death data or adult firearm injury data, but few studies have analyzed firearm injury data specifically among youth. To inform the current debate surrounding gun policy in the United States, this study aims to provide an estimate of the immense burden of youth firearm injury and its associated risk factors. Therefore, we performed a descriptive analysis of the Nationwide Emergency Department Sample, the largest all-payer emergency department database (...) in the United States, from January 2006 to September 2015. All patients age < 21 who presented with any diagnosis of firearm-related injuries were included. There were an estimated 198,839 incidents of firearm-related emergency department visits for patients age < 21 from 2006 through 2015. After presenting to the ED, an estimated 11,909 cases resulted in death. The population adjusted rate of firearm-related emergency department visits was highest in the South and Midwest. This study demonstrates the significant burden of firearm injury among youth. Having a reliable estimate of the number of children harmed by firearms each year is a critical tool for policymakers — and may make common-sense gun safety measures more politically possible. (shrink)

We address anticipated fermion–antifermion and dimension-4 gauge-field vacuum-condensate contributions to the magnetic portion of the fermion–photon vertex function in the presence of a vacuum with nonperturbative content, such as that of QCD. We discuss how inclusion of such condensate contributions may lead to a vanishing anomalous magnetic moment, in which case vacuum condensates may account for the apparent consistency between constituent quark masses characterizing baryon magnetic moments and those characterizing baryon spectroscopy.

Inclusive single jet production in hadron collisions is considered. It is shown that the QCD parton model predicts a nonmonotonic dependence of the inclusive cross section on the fraction of the energy deposited in the jet registered, if it is normalized on the same cross section measured at another collision energy. Specifically, if the cross section is normalized by the one measured at a higher collision energy, it possesses a minimum which depends on jet rapidity. This prediction can be tested (...) at the Fermilab Tevatron, at the CERN LHC, and at the Very Large Hadron Collider under discussion. (shrink)

We investigate the complexity of finding solutions to infinite recursive constraint satisfaction problems. We show that, in general, the problem of finding a solution to an infinite recursive constraint satisfaction problem is equivalent to the problem of finding an infinite path through a recursive tree. We also identify natural classes of infinite recursive constraint satisfaction problems where the problem of finding a solution to the infinite recursive constraint satisfaction problem is equivalent to the problem of finding an infinite path through (...) finitely branching recursive trees or recursive binary trees. There are a large number of results in the literature on the complexity of the problem of finding an infinite path through a recursive tree. Our main result allows us to automatically transfer such results to give equivalent results about the complexity of the problem of finding a solution to a recursive constraint satisfaction problem. (shrink)

This book provides much new thinking on the phenomenon of whole person education, a phenomenon which features strongly in East Asian universities, and which aims to develop students intellectually, spiritually, and ethically, to master critical thinking skills, to explore ethical challenges in the surrounding community and to acquire a broad based foundation of knowledge in humanities, society and nature. The book considers different approaches to whole person education, including Confucian, Buddhist, and Chinese perspectives, Western philosophy and religion and interdisciplinary approaches. (...) Overall, the book provides a comprehensive overview of whole person education, why it matters and how to implement it. Moreover, although the examples in the book are from East Asia, the discussion and the values involved are universal, important for the whole world. (shrink)

There is a trend toward the use of predictive systems in communications networks. At the systems and network management level predictive capabilities are focused on anticipating network faults and performance degradation. Simultaneously, mobile communication networks are being developed with predictive location and tracking mechanisms. The interactions and synergies between these systems present a new set of problems. A new predictive network management framework is developed and examined. The interaction between a predictive mobile network and the proposed network management system is (...) discussed. The Rapidly Deployable Radio Network is used as a specific example to illustrate these interactions. (shrink)

Our goal is to use prototype analysis to distinguish the folk or culturally held understandings of love, romantic love, and sex and to specify, from the obtained data, the semantic relationship among these three associated concepts. By considering the semantic distinctions between these three concepts, we come to an unintended insight: if romantic love is a socio-cultural universal it does not appear to have the same evolutionary history as love or sex and this may account for its somewhat ambiguous status (...) in the scholarly literature on romantic love. We demonstrate that, in the United States, sex, in and of itself, is seldom conceived of as a relationship while love and romantic love are primarily viewed as relational. Our findings, though preliminary, strongly suggest that romantic love is a synthesis of two evolutionary drives: love and sex. (shrink)

RESUMEN Una vez que el foco de la reflexión pasa de las teorías ideales a la aplicación de la justicia social, centrada en las instituciones de las sociedades democráticas, se requiere prestar especial atención a los estilos de vida. Estos tienen una alta incidencia en cómo la justicia es realizada y afectan tanto a la desigualdad económica como a la disponibilidad de los recursos naturales. En nuestras sociedades es posible establecer restricciones a los estilos de vida, especialmente en aquellos casos (...) en que, por el efecto de algunas dinámicas sociales, aquellos se desacoplan de las concepciones del bien. Se defiende que, en tales casos, la base normativa que permite exigir el respeto a los estilos de vida se disuelve y por ello es posible justificar su restricción. ABSTRACT Now that the focus of reflection has shifted from ideal theories to the application of social justice, centered on the institutions of democratic societies, it is necessary to pay special attention to lifestyles, since they not only influence the realization of justice, but also have an effect on economic inequality and the availability of natural resources. In our societies, it is possible to place restrictions on lifestyles, especially in those cases in which, influenced by certain social dynamics, they disengage from conceptions of the good. The article argues that, in those cases, the normative base grounding the demand that lifestyles be respected is dissolved, thus justifying their restriction. (shrink)

The topology of DNA duplexes changes during replication and also after deproteinization in vitro. Here we describe these changes and then discuss for the first time how the distribution of superhelical stress affects the DNA topology of replication intermediates, taking into account the progression of replication forks. The high processivity of Topo IV to relax the left‐handed (+) supercoiling that transiently accumulates ahead of the forks is not essential, since DNA gyrase and swiveling of the forks cooperate with Topo IV (...) to accomplish this task in vivo. We conclude that despite Topo IV has a lower processivity to unlink the right‐handed (+) crossings of pre‐catenanes and fully replicated catenanes, this is indeed its main role in vivo. This would explain why in the absence of Topo IV replication goes‐on, but fully replicated sister duplexes remain heavily catenated. (shrink)

El artículo presenta el desarrollo básico del comentario agustiniano al pasaje de Timeo 41 A-B, para posteriormente recensionar la crítica provocada por la interpretación agustiniana, y finalmente expone sucintamente, la doctrina agustiniana del cuerpo espiritual.

This paper describes the design of a control and management network (orderwire) for a mobile wireless Asynchronous Transfer Mode (ATM) network. This mobile wireless ATM network is part of the Rapidly Deployable Radio Network (RDRN). The orderwire system consists of a packet radio network which overlays the mobile wireless ATM network, each network element in this network uses Global Positioning System (GPS) information to control a beamforming antenna subsystem which provides for spatial reuse. This paper also proposes a novel Virtual (...) Network Configuration (VNC) algorithm for predictive network configuration. A mobile ATM Private Network-Network Interface (PNNI) based on VNC is also discussed. Finally, as a prelude to the system implementation, results of a Maisie simulation of the orderwire system are discussed. (shrink)

This paper extends a stochastic theory for buffer fill distribution for multiple “on‘ and “off‘ sources to a mobile environment. Queue fill distribution is described by a set of differential equations assuming sources alternate asynchronously between exponentially distributed periods in “on‘ and “off‘ states. This paper includes the probabilities that mobile sources have links to a given queue. The sources represent mobile user nodes, and the queue represents the capacity of a switch. This paper presents a method of analysis which (...) uses mobile parameters such as speed, call rates per unit area, cell area, and call duration and determines queue fill distribution at the ATM cell level. The analytic results are compared with simulation results. (shrink)

Besides sensory characteristics of food, food-evoked emotion is a crucial factor in predicting consumer’s food preference and therefore in developing new products. Many measures have been developed to assess food-evoked emotions. The aim of this literature review is (i) to give an exhaustive overview of measures used in current research and (ii) to categorize these methods along measurement level (physiological, behavioral, and cognitive) and emotional processing level (unconscious sensory, perceptual / early cognitive, and conscious / decision making) level. This 3x3 (...) categorization may help researchers to compile a set of complementary measures (‘toolbox’) for their studies. We included 101 peer-reviewed articles that evaluate consumer’s emotions and were published between 1997 to 2016, providing us with 59 different measures. More than 60% of these measures are based on self-reported, subjective ratings and questionnaires (cognitive measurement level) and assess the conscious / decision-making level of emotional processing. This multitude of measures and their overrepresentation in a single category hinders the comparison of results across studies and building a complete multi-faceted picture of food-evoked emotions. We recommend (1) to use widely applied, validated measures only, (2) to refrain from using (highly correlated) measures from the same category but use measures from different categories instead, preferably covering all three emotional processing levels, and (3) to acquire and share simultaneously collected physiological, behavioral, and cognitive datasets to improve the predictive power of food choice and other models. (shrink)

In the present paper, these authors argue on actual reasons why Hilbert’s axiomatic program to unify gravitation theory and electromagnetism failed completely. An outline of plausible resolution of this problem is given here, based on: a) Gödel’s incompleteness theorem, b) Newton’s aether stream model. And in another paper we will present our calculation of receding Moon from Earth based on such a matter creation hypothesis. More experiments and observations are called to verify this new hypothesis, albeit it is inspired from (...) Newton’s theory himself. (shrink)

Despite its enormous practical success, many physicists and philosophers alike agree that the quantum theory is full of contradictions and paradoxes which are difficult to solve consistently. Even after 90 years, the experts themselves still do not all agree what to make of it. The area of disagreement centers primarily around the problem of describing observations. Formally, the so-called quantum measurement problem can be defined as follows: the result of a measurement is a superposition of vectors, each representing the quantity (...) being observed as having one of its possible values. The question that has to be answered is: how this superposition can be reconciled with the fact that in practice we only observe one value. How is the measuring instrument prodded into making up its mind which value it has observed? Among some alternatives to resolve the above QM measurement problem, a very counterintuitive one was suggested by Hugh Everett in his 1955 Princeton dissertation, which was subsequently called the Many-Worlds Interpretation of QM (MWI). In this paper we will not discuss all possible scenarios to solve the measurement problem, but we will only shortly discuss Everett’s MWI, because it has led to heated debates on possibility of multiverses, beyond the Universe we live in. We also discuss two alternatives against MWI proposal: (a) the so-called scale symmetry theory, (b) the Maxwell-Dirac isomorphism. In last section, we also discuss shortly MWI hypothesis from philosophical perspective. (shrink)

In the present paper we discuss: a) how Hilbert’s unification program failed completely, and b) we outline a new electron model based on Helmholtz’s electron vortex and Kolmogorov theory of turbulence. Novelty aspect: we discuss among other things, electron capture event, and von Karman vortex street. We also discuss a new model of origination of charge and matter. This paper is a sequel to a preceding paper on similar theme.

To emphasize what we have outlined in a preceding paper, we consider the following: that human consciousness model should take into consideration “spirit” role, i.e. the mind-body-spirit as integral aspect, which view is neglected in the so-called Freudian mental model. In this paper, we consider two approaches to cancer treatment derived from such an integral triune view of human consciousness, including (a) healing frequency approach as advised by Royal Rife and David Hawkins, and also (b) relational therapy, based on recent (...) research on the healing role of love and compassion. (shrink)

While it is known that Euclid’s five axioms include a proposition that a line consists at least of two points, modern geometry avoid consistently any discussion on the precise definition of point, line, etc. It is our aim to clarify one of notorious question in Euclidean geometry: how many points are there in a line segment? – from discrete-cellular space (DCS) viewpoint. In retrospect, it may offer an alternative of quantum gravity, i.e. by exploring discrete gravitational theories. To elucidate our (...) propositions, in the last section we will discuss some implications of discrete cellular-space model in several areas of interest: (a) cell biology, (b) cellular computing, (c) Maxwell equations, (d) low energy fusion, and (e) cosmology modelling. (shrink)